James Coleman
Chemical Structures
Lewis Dot
Chiral= Attached to 4 different elements or groups
Below is a drawing of morphine's structure, the largest difference between the planes is indicated by the dashed lines between two of the carbon atoms.
Bond Strength(weakest to strongest): C-N < C-C < C-O < C-H < O-H < C=C
Bond Length (longest to shortest): C-C, C-N, C-O ,C=C, C-H, O-H
With C-N being the longest and O-H being the shortest
Double bonds are stronger bonds because they pull the two atoms closer together, so the strongest bond is between C=C
Single bonds are usually shorter and weaker, but O-H is shortest because of the strong Hydrogen bond, so it's closer even though it's not stronger than C=C. And C-H is shorter than C=C because H is smaller so theres less e- repulsion and the size itself is smaller.
Below is a drawing of morphine's structure, the largest difference between the planes is indicated by the dashed lines between two of the carbon atoms.
Bond Strength(weakest to strongest): C-N < C-C < C-O < C-H < O-H < C=C
Bond Length (longest to shortest): C-C, C-N, C-O ,C=C, C-H, O-H
With C-N being the longest and O-H being the shortest
Double bonds are stronger bonds because they pull the two atoms closer together, so the strongest bond is between C=C
Single bonds are usually shorter and weaker, but O-H is shortest because of the strong Hydrogen bond, so it's closer even though it's not stronger than C=C. And C-H is shorter than C=C because H is smaller so theres less e- repulsion and the size itself is smaller.
Space Filling
Red= Oxygen
Grey=Carbon
Blue=Nitrogen
White=Hydrogen
Electropositive Regions=Hydrogen (white)
Electronegative Regions= Nitrogen(blue) and Oxygen(red)
Grey=Carbon
Blue=Nitrogen
White=Hydrogen
Electropositive Regions=Hydrogen (white)
Electronegative Regions= Nitrogen(blue) and Oxygen(red)
Morphine Binding to Opioid Receptors
Green-morphine
Pale Yellow- Opiate Receptor on right terminal
Blue-Dopamine released from left terminal
Purple- dopamine receptors
Pale Yellow- Opiate Receptor on right terminal
Blue-Dopamine released from left terminal
Purple- dopamine receptors